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Dr Jamil Jubrail, Lecturer

Dr Jamil Jubrail
PhD

Lecturer

Biography

Jamil graduated with a master’s degree in Biochemistry and Microbiology from the University of Sheffield in 2010.

In 2014 he was awarded his PhD from the University of Sheffield where he identified how Staphylococcus aureus hijacked human macrophages in order to survive and spread to distant sites. Following this he moved to the Institut Cochin in Paris to undertake post-doctoral research, in collaboration with AstraZeneca, exploring how rhinovirus perturbed airway macrophage functions preventing their ability to control secondary bacterial infection. Dr Jubrail described new mechanisms used by rhinovirus to disrupt macrophage functions and identified for the first time key proteins targeted by the virus to affect the cell’s functions. He also implicated new cellular functions for these proteins.

He then moved to the University of Edinburgh to carry out further post-doctoral training, where he evaluated the therapeutic potential of host defence peptides and different inducers of these peptides during respiratory syncytial virus (RSV) infection of human epithelial cells.

In 2021 Jamil moved to Solent University to begin a new lectureship position and establish his own research group. He is also an active member within respiratory societies including the European Respiratory Society (ERS) and serves as a reviewer for the European Board for Accreditation in Pneumology (EBAP) as well as a peer reviewer for numerous journals and societies.

Further information

2020

Best A*, Jubrail J*, Boots M, Dockrell D, Marriott H (A mathematical model shows macrophages delay Staphylococcus aureus replication, but limitations in microbicidal capacity restrict bacterial clearance) Journal of Theoretical Biology, 2020, July 497: 110256 *joint first authorship

Jubrail J, Africano-Gomez K, Herit F, Mularski A, Bourdoncle P, Oberg L, Israelsson E, Burgel PR, Mayer G, Cunoosamy D, Kurian N, Niedergang F (Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus). EMBO reports, 2020, Jan 21(1): e47963

2019

Preston JA, Bewley MA, Marriott HM, McGarry Houghton A, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH (Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia). American journal of respiratory and critical care medicine, 2019, July 200(1): 84-97

2018

Jubrail J, Africano-Gomez K, Herit F, Baturcam E, Mayer G, Cunoosamy DM, Kurian N, Niedergang F (HRV16 Impairs Macrophages Cytokine Response to a Secondary Bacterial Trigger). Frontiers in immunology, 2018, December 9: 2908

2017

Jubrail J, Kurian N, Niedergang F (Macrophage phagocytosis cracking the defect code in COPD). Biomedical journal, 2017, December 40(6): 305-312

Almendros I, Bartel S, Bostantzoglou C, Jubrail J, Lehmann M, Wagner D (Early Career Members at the ERS LSC 2017: mechanistic overlap between chronic lung injury and cancer). Breathe (Sheffield, England), 2017, December 13(4): 323-326 All authors had equal authorship.

2016

Jubrail J, Morris P, Bewley MA, Stoneham S, Johnston SA, Foster SJ, Peden AA, Read RC, Marriott HM, Dockrell DH (Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages).Cellular microbiology, 2016, Jan 18(1): 80-96

2014

Cole J, Aberdein J, Jubrail J, Dockrell DH (The role of macrophages in the innate immune response to Streptococcus pneumoniae and Staphylococcus aureus: mechanisms and contrasts). Advances in microbial physiology, 2014, November, 65: 125-202

Taught courses

BSc (Hons) Biomedical Science

Biomedical scientists play a leading role in developing our knowledge of human illness. As a biomedical science student here at Solent, you’ll build a detailed understanding of...